XA AM3A-E13

High-performance AI computing with air-cooled flexibility

Powered by AMD Instinct™ MI355X GPUs with EPYC™ processors

ASUS XA AM3A-E13 is a 10U air-cooled AI server powered by eight AMD Instinct™ MI355X GPUs and dual AMD EPYC™ 9005/9004 Series processors. Built for demanding AI inference, training, and HPC workloads, it combines high-performance GPU acceleration, expansive memory capacity, and PCIe 5.0 connectivity with a modular, service-friendly design. Its optimized air-cooled architecture enables flexible deployment in existing data centers without requiring direct liquid cooling infrastructure.

  • AI Computing
    Performance

    8 x MI355X GPUs

  • Flexible
    Deployment

    Air cooled

  • Enterprise
    Scalability

    Dual AMD EPYC™ CPUs,
    PCIe 5.0 & modular design

Front view of the ASUS XA AM3A-E13 10U air-cooled GPU server with a multi-fan chassis and front drive bays

A New Generation of AMD Instinct™ Performance

AMD Instinct™ MI355 vs. MI325

Built on AMD CDNA™ 4 architecture, the AMD Instinct™ MI355X advances AI computing with faster GPU-to-GPU communication, expanded HBM3E memory, and nearly 2× FP8 compute throughput compared with the previous generation. With native MXFP6 and MXFP4 support, MI355X further strengthens low-precision AI processing capabilities, offering a compelling compute option for large-scale generative AI and inference workloads.
AMD Instinct MI355X accelerator hardware used in the ASUS XA AM3A-E13 eight-GPU server.
  • +33% VS. MI325
    GPU-to-GPU Bandwidth
  • +12.5% VS. MI325
    HBM3E Memory Capacity
  • 1.9 X VS. MI325
    FP8 Dense Performance
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PCIe 5.0 Expansion

High-speed I/O for storage and networking​

ASUS XA AM3A-E13 features 11 PCIe 5.0 expansion slots, including eight PCIe 5.0 x16 slots connected through the GPU-group switch architecture. With additional expansion options for networking and storage adapters, the system offers flexible I/O configurations to accommodate data-intensive AI and HPC workloads.​
PCIe generation speed comparison
Cutaway view of XA AM3A-E13 showing its eight-GPU air-cooled chassis, modular service access, and storage-to-GPU-to-NIC connectivity. Cutaway view of XA AM3A-E13 showing its eight-GPU air-cooled chassis, modular service access, and storage-to-GPU-to-NIC connectivity.

288GB HBM3E and 8TB/s memory bandwidth per OAM (Open Accelerator Module)

1:1:1 connectivity between storage, GPU and NIC

Modular, tool-free design for simplified maintenance

Purpose-built 10U air-cooled architecture for 8 MI355X GPUs

XA AM3A-E13 front panel showing cooling fans, eight 2.5-inch NVMe bays, dual 10GbE ports, management port, USB, VGA, and power button. XA AM3A-E13 front panel showing cooling fans, eight 2.5-inch NVMe bays, dual 10GbE ports, management port, USB, VGA, and power button.

15 x 80*80 Fan For AMD MI355X 8-GPU Baseboard

8 x 2.5" NVMe

2x 10Gb RJ45 Lan Port

1x Mgmt Port

1x VGA port

4x USB3.2 Gen1 ports

1x Power Button

XA AM3A-E13 rear panel identifying the 6U GPU sled, 4U CPU sled, PCIe 5.0 expansion slots, power supplies, and service controls. XA AM3A-E13 rear panel identifying the 6U GPU sled, 4U CPU sled, PCIe 5.0 expansion slots, power supplies, and service controls.

GPU Sled
(6U)

CPU Sled
(4U)

2 x 2.5"NVMe/SATA*/SAS*
*RAID/HBA card required.

1 x PCIe Gen5 x 8 FHHL + 1 x PCIe Gen5 x 16, FHHL

6+2 3200W 54V CRPS

1x Locate Button

1x Power Button

GPU Sled Handle

8 x PCIe Gen5 x 16, LP

1 x PCIe Gen5 x 16, FHHL

Eight AMD Instinct MI355X GPUs

Built for large-scale AI inference and training

Featuring eight AMD Instinct™ MI355X accelerators based on AMD CDNA™ 4 architecture, XA AM3A-E13 offers up to 288GB of HBM3E memory and 8TB/s bandwidth per GPU, providing the computational resources to handle increasingly complex AI models and memory-intensive workloads.
Internal view of the ASUS XA AM3A-E13 showing eight AMD Instinct MI355X GPUs installed in the server chassis.

Balanced GPU-to-NIC Connectivity

1:1:1 connection between storage, GPU and NIC

XA AM3A-E13 features a 1:1:1 connectivity architecture linking storage, GPUs and NICs through PCIe 5.0 switches. Combined with AMD Infinity Fabric™ interconnects across eight MI355X GPUs, this design facilitates efficient data movement and high-bandwidth communication for distributed AI training and data-intensive workloads.
Internal XA AM3A-E13 architecture illustrating high-bandwidth connections between MI355X GPUs, network interfaces, and storage.

AMD ROCm™ open software platform

An open ecosystem for AI development and deployment

Powered by the AMD ROCm™ software ecosystem, the AMD Instinct™ MI355X GPUs in ASUS XA AM3A-E13 offer compatibility with leading AI frameworks and inference engines, including PyTorch, TensorFlow, JAX, vLLM and SGLang. ROCm simplifies model migration, training and inference workflows, helping developers deploy AI applications with minimal code changes across enterprise AI and HPC environments.
Software stack linking PyTorch, TensorFlow, JAX, vLLM, and SGLang through AMD ROCm to the MI355X GPU platform.

Air Cooling Solution

10U air-cooled architecture for flexible data center deployment

ASUS XA AM3A-E13 features a purpose-built 10U air-cooled chassis designed to accommodate eight AMD Instinct dual AMD EPYC MI355X GPUs and processors with up to 400W CPU TDP. Its dedicated cooling system manages the thermal demands of intensive AI workloads without requiring direct liquid cooling infrastructure, offering greater deployment flexibility for existing data centers.
Airflow illustration of the XA AM3A-E13 10U chassis, with cool air entering the front and warm air exhausting upward through the GPU system.
Airflow illustration of the XA AM3A-E13 10U chassis, with cool air entering the front and warm air exhausting upward through the GPU system.

Serviceability

Simplified maintenance for efficient IT operations

Clearly Marked Service Access
  • Technician accessing a 60 mm fan module in the XA AM3A-E13 chassis.

    60 fan module

  • Rear riser module access point in the XA AM3A-E13 server.

    Rear riser module

  • Removable NIC riser module for XA AM3A-E13 service access.

    Nic riser module

Tool-Free Component
  • Technician removing the XA AM3A-E13 NIC riser module without tools.

    Nic riser module

  • Technician servicing the XA AM3A-E13 front I/O module.

    Front IO module

  • Technician removing an 80 mm cooling fan module from the XA AM3A-E13.

    80 fan module

  • Hand operating a plunger release mechanism for tool-free XA AM3A-E13 maintenance.

    Plungers

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Management

Comprehensive IT infrastructure solutions

Advanced ASUS management tools comprise IT assets management, security and reliability to improve the performance, up-time and real-time monitoring of the servers remotely — highly increasing the efficiency of IT infrastructure.

BMC

Remote server management

ASUS ASMB11-iKVM is the latest server-management solution from ASUS, built upon the ASPEED 2600 chipset running on the latest AMI MegaRAC SP-X. The module provides various interfaces to enable out-of-band server management through WebGUI, Intelligent Platform Management Interface (IPMI) and Redfish® API.
Learn more
BMC boot-time chart comparing AST2600 at 12.885 seconds and AST2500 at 21.262 seconds, showing a 39% faster boot time.

IT infrastructure-management software

Streamline IT operations via a single dashboard

ASUS Control Center Data Center Edition is remote IT-management software application designed for monitoring hardware and software IT assets and inventory status, and enabling seamless remote BIOS configurations and updates, efficient IT diagnostics and troubleshooting and enhanced security with hotfix updates — allowing easier server management for any IT infrastructure.
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ASUS Control Center Data Center Edition dashboards displayed across desktop and mobile management screens.

Trusted Platform Module 2.0

ASUS servers also include support Trusted Platform Module 2.0 (TPM 2.0) to secure hardware through integrated cryptographic keys and offer regular firmware update for vulnerabilities.
Learn More about the product support list

Performance

Dual AMD EPYC™ 9005/9004 Series processors

ASUS XA AM3A-E13 integrates two AMD EPYC™ processors to handle CPU-intensive tasks and coordinate data movement across GPU, networking and storage resources. With support for up to 400W CPU TDP and 128 PCIe lanes per processor, the platform provides the processing capacity and I/O connectivity required for demanding AI and HPC environments.

  •  

    128

    Max CPU Cores

  •  

    384

    Max L3 Cache

  •  

    128

    PCIe Lanes per CPU

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FAQs

  • What are the key features of the AMD Instinct™ MI355X GPUs in ASUS XA AM3A-E13?
    What are the key features of the AMD Instinct™ MI355X GPUs in ASUS XA AM3A-E13? ASUS XA AM3A-E13 features eight AMD Instinct™ MI355X GPUs built on AMD CDNA™ 4 architecture. Each GPU offers 288GB of HBM3E memory, up to 8TB/s memory bandwidth, and support for AI-optimized precision formats including MXFP4 and MXFP6. The eight-GPU platform provides 2.3TB of aggregate GPU memory for large-scale AI inference, training, and HPC workloads.