System Layout
Block Diagram
This is a line graph that helps you understand the locations of the key components on this motherboard

1 1 x MLAN

2 2 x USB 3.2 Gen1

3 1 x VGA Port

4 Broadcom BCM57414B1KFSBG

5 2 x SFP28 25Gb/s

6 TPM header

7 1 x PCI-E x8 (Gen5 x 8Link)
8 2 x PCI-E x16 (Gen5 x 16Link)
9 Aspeed AST2600
management controller

10 1 x MCIO Gen5x8 (SATA or NVMe)

11 4 x MCIO Gen5x8 (NVMe)

12 AMD LGA 4844P Socket SP6

13 12 x DIMM slots support

14 1x M.2 Socket, up to 2280

15 1x M.2 Socket, up to 22110

This is S14NA-U12's block diagram, illustrating its key components and functionality for easy understanding
Powered by AMD EPYCTM 8004 processors

The ASUS S14NA-U12 leverages the impressive performance and streamlined platform componentry of EPYC 8004 processors using the new SP6 socket, enabling original equipment manufacturers (OEMs) to offer cost-effective, business-relevant server configurations. The adherence to industry standards in platform management, coupled with top-tier security features and energy efficiency of the EPYC 8004-series processors, significantly reduces operational costs compared to power-hungry, non-standard alternatives. Customers can expect best-in-class total cost of ownership (TCO) across numerous deployments with systems based on AMD EPYC 8004 processors.

This is the AMD EPYC™ 8004-series processor, codenamed Siena.
64 Cores
SP6 Socket
6 Channels
225 W TDP
Dual SFP28 25-gigabit Ethernet with teaming support

The S14NA-U12 provides ultra-high-speed network connectivity, with each SFP28 25-gigabit Ethernet connection offering up to 25 Gbps bandwidth, vastly outperforming traditional gigabit Ethernet. This speed enhances data-traffic handling, thereby improving application performance. Additionally, it ensures reliability through teaming support, where multiple network interface cards (NICs) combine for enhanced redundancy, minimizing service interruptions. The server's low-latency SFP28 technology is crucial for real-time applications like high-frequency trading and video conferencing.

A motherboard with two Ethernet ports, emitting beams of light from them.
Flexible expandability

The S14NA-U12 also boasts five MCIO slots, with MICO5 supporting both NVMe and SATA devices  . This design offers versatile storage options, allowing users to choose between NVMe and SATA drives to meet a variety of storage needs. Additionally, it ensures high performance with support for NVMe drives, making it ideal for data-intensive applications like databases and high-performance computing.

S14NA-U12’s scalability is another standout feature, as it can accommodate up to 10 NVMe drives — providing ample storage capacity that can readily expand to meet the growing demands of data-intensive operations. Up to two dual-slot GPUs are also supported.

A motherboard with five MCIO slots highlighted with yellow boxes
Comprehensive IT infrastructure management

S14NA-U12 features an embedded iKVM module and is optionally equipped with ASUS Control Center, offering comprehensive out-of-band and in-band management features tailored for small and mid-size businesses. The embedded ASUS ASMB11-iKVM module supports remote BIOS updates, fan control, standalone KVMs, video recording and BSOD capture, providing around-the-clock remote monitoring and diagnostics. This functionality remains accessible even if the operating system is down or offline, through a user-friendly web-based graphical interface compatible with all major browsers. ASUS Control Center (ACC) further enhances IT infrastructure management, centralizing and integrating monitoring and control for ASUS commercial products, including servers, workstations, and digital signage. ACC enables remote BIOS updates, mobile device system monitoring, and simplified server management through one-click software updates and dispatching.

Learn more about ASUS Control Center

Watch the video

A tablet, a monitor, and a smartphone, all displaying the ASUS Control Center interface.
ASUS ProCool
Quick initialization
Visible Q-Code
OS drive installation
and debugging
ASUS ProCool connector

ASUS ProCool power connectors are designed without any hollow areas, enabling lower impedance, faster heat dissipation and cooler operating temperatures for reduced power loss and increased cost savings.

This is a schematic top view of a ProCool connector. It consists of a rectangle with three squares and three hexagons inside
Quick initialization guidance

The S14NA-U12 provides instant system information during initialization and reports any unusual diagnostic results for more efficient IT operation and easy troubleshooting.

Two black screens, with the left screen displaying 'ASUS' and the right screen showing system information
Visible Q-Code

The S14NA-U12 has a visible Q-Code/port 80 LED display for simple monitoring of the entire boot process, from powering on through loading the operating system.

A rectangular LED display with two blue 0s in the middle.
OS drive installation and debugging

An internal USB 3.2 port accepts boot disks, providing a safer way to install Linux or VMware Hypervisor as well as additional access for debugging.

A USB flash drive with a blue USB symbol on it
MicroSD card support

A BMC (baseboard management controller) supports microSD cards to facilitate remote OS updates, image file and video storage, and log data tracking.

MicroSD card support