Accelerate performance for HPC and AI workloads

Eight dual-slot GPU compute in 4U

ESC8000A-E12P is an AMD EPYC™ 9004 dual-socket server built for the demands of enterprise AI infrastructure to deliver unprecedented performance with industry-leading GPUs, faster GPU interconnect and higher-bandwidth fabric, and supports up to eight dual-slot active or passive GPUs scalable configuration with a choice of NVIDIA NVLink® Bridge or AMD Infinity Fabric™ Link to enable scaling of performance with increased bandwidth — ready to match your AI and HPC workloads.
  • AMD EPYC logo
  • NVIDIA certified logo
  • AMD Instinct logo
  • AMD Xilinx logo
ESC8000A-E12P server
System layout System layout

8 x PCIe x16 slots (Gen5, FHFL) for dual-slot GPU card
4 x PCIe slot (Gen5, x16 link) for NIC card
1 x PCIe slot (Gen5, x16 link) for OCP socket option (will occupy one PCIe Slot)


2 x AMD EPYC 9004 processor (Up to 400W)

8 x 3.5”/2.5” Hot-swap storage bays
(backplane supports up to 8 x NVMe/SATA/SAS*)

2+1, 2+2 Redundant 2600W~3000W 80 PLUS Titanium CRPS

1 x PCIe x16 slot (Gen5 x8 link, LP, HL) for HBA/RAID card)

* SAS support required a HBA/RAID card.

Front panel layout Front panel layout

Front I/O

1 x PCIe x16 slot (Gen5 x16 link, LP, HL) for HBA/RAID card

8 x 3.5”/2.5” hot-swap drive bays

Rear panel layout Rear panel layout

8 x PCIe x16 slots (Gen5, FHFL) for dual-slot GPU card
4 x PCIe slot (Gen5, x16 link) for NIC card
1 x PCIe slot (Gen5, x16 link) for OCP socket option (will occupy one PCIe Slot)

Management LAN

VGA & COM ports

2 x 10GbE LAN ports (X710-AT2) Or
2 x Gigabit LAN ports (I350-AM2)

2+1, 2+2 Redundant 2600W~3000W 80 PLUS Titanium CRPS

PCIe 5.0 Switch Solution


PCIe 5.0 Switch Solution

This server features the latest Broadcom PEX8900 series of switches, supporting up to 1,024 Gbps (128 GBps) of raw bandwidth per port (x16) to create high-availability hyper-scale systems. It uses the PCI Express® 5.0 bus to empower communication between in-rack hosts and endpoints, simplifying connectivity while providing the highest PCIe switching performance available for data center servers, storage and networks. Take advantage of these industry-first features today for the most demanding hyper-converged AI/ML/DL applications.

MLPerf Benchmarks

Top results on AI workloads

ASUS NVIDIA-Certified GPU servers have achieved top performance results in the data-center Closed division across six tasks on MLCommons® MLPerf™ training and inference benchmarks, outperforming other servers with the equivalent GPU configurations to create complete, optimized solutions and cultivate strong industry partnerships to enhance AI developments in diverse fields to push technology to its limits.
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Optimized Thermal Design

Independent CPU and GPU airflow tunnels

Our servers features a streamlined design with dedicated CPU and GPU airflow tunnels for seriously efficient heat dissipation. This advanced design provides better cooling for both the GPU and CPU, enabling heat to be expelled into the surrounding ambient air for greater energy efficiency and overall savings on system power.
GPU and CPU Airflow tunnel
A close look at GPU fans

2+2 Power Supplies

Up to 96% efficient for reduced operating costs

ESC8000A-E12P supports up to four 3000 W 80 PLUS® Titanium redundant power supplies to reduce operating costs and enable easier servicing. When four power supplies are installed, the configuration can be set to redundant with 2+2 or 2+1 models. This ensures power is supplied to the system equally from all power supplies to maximize efficiency, enabling uninterrupted operation.
The rear panel with four power supplies
The front/rear panel of 5 PCIe + 4 NVMe layout The front/rear panel of 5 PCIe + 4 NVMe layout

4 x NVMe (Gen5, x16 link)

1 x PCIe slot (Gen5 x16 link, LP, HL) for HBA/RAID card

1 x PCIe slot (Gen5, x16 link) for NIC

2 x PCIe slots (Gen5, x16 link) for NIC

1 x PCIe slot (Gen5, x16 link) for NIC

The front/rear panel of 4 PCIe + 1 OCP 3.0 layout The front/rear panel of 4 PCIe + 1 OCP 3.0 layout

1 x PCIe slot (Gen5 x16 link, LP, HL) for HBA/RAID card

1 x OCP3.0 socket board (Gen5 x16 link)

2 x PCIe slots (Gen5, x16 link) for NIC

1 x PCIe slot (Gen5, x16 link) for NIC


Remote server management

ASUS ASMB11-iKVM is the latest server-management solution from ASUS, built upon the ASPEED 2600 chipset running on the latest AMI MegaRAC SP-X. The module provides various interfaces to enable out-of-band server management through WebGUI, Intelligent Platform Management Interface (IPMI) and Redfish® API.
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ASUS BMC boot time comparison

IT infrastructure-management software

Streamline IT operations via a single dashboard

ASUS Control Center (ACC) is remote IT-management software application designed for monitoring hardware and software IT assets and inventory status, and enabling seamless remote BIOS configurations and updates, efficient IT diagnostics and troubleshooting and enhanced security with hotfix updates — allowing easier server management for any IT infrastructure.
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ASUS Control Center software on desktop, tablet and mobile device

Hardware Root-of-Trust Solution

Detect, recover, boot and protect

ASUS servers integrate PFR FPGA as the platform Root-of-Trust solution for firmware resiliency to prevent from hackers from gaining access to infrastructure. ASUS security solutions are fully compliant with the 2018 National Institute of Standards and Technology (NIST) SP 800 193 specification.

* Platform Firmware Resilience (PFR) module must be specified at time of purchase and is factory-fitted. It is not for sale separately.

Trusted Platform Module 2.0

ASUS servers also include support Trusted Platform Module 2.0 (TPM 2.0) to secure hardware through integrated cryptographic keys and offer regular firmware update for vulnerabilities.
Learn More about the product support list


NVIDIA® solutions for 3D collaboration

NVIDIA Omniverse partnership
NVIDIA is dedicated to its partners and believes that a strong partnership is the foundation of mutual success.
NVIDIA Omniverse logo
Full ASUS product lineup for Omniverse Enterprise
ASUS has the world’s best PCs, servers, monitors and graphics cards. With an expanding range of superior content-creation and gaming products, ASUS leads the industry through innovation to create the most ubiquitous, intelligent productivity.
ASUS Omniverse product overview
Strong partnership with 3D partners
Connect to the top industry apps your teams use every day, with plug-ins that enable live-sync collaboration and iteration across multiple software suites simultaneously — all brought together in Omniverse Enterprise.
Omniverse partner logo set
Success cases
Reduce deployment risks with a complete suite of VMware data-center products for Omniverse Enterprise.
Mooshine XR studio logoReallusion logo


Improved IT operational efficiency

  • Tool-less cover

    Tool-less Cover

    ASUS servers feature three easy-access covers that can be opened without tools, enabling IT staff to perform maintenance on specific components without removing the server fully from the rack.

  • Front-bezel Q-Code

    Front-bezel Q-Code

    ASUS servers have a visible Q-Code/port-80 LED display LED for simple monitoring of the entire boot process, from power on through loading of the operating system.

  • Hot-swap design

    Hot-swap design

    ASUS servers feature multiple hot-swap components, including fans, power supplies and storage for easy troubleshooting to keep 24/7 seamless operations.


AMD EPYC 9004 series processors

ASUS and AMD work together to offer the latest EPYC 9004 servers that drive high performance, whether you need lightweight dual processors or building an exascale supercomputing of data centers. The AMD EPYC 9004 processors offer up to 96 Zen 4 cores with 12 channel DDR5 and PCIe 5.0 expansion.
  • Up to


    Zen 4c cores

  • Up to


    L3 Cache

    with AMD 3D V-Cache technology

  • 128/160

    (1 socket/2 socket)

    PCIe 5.0

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